View source for 5qi8


==PanDDA analysis group deposition -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000605a==
<StructureSection load='5qi8' size='340' side='right'caption='[[5qi8]], [[Resolution|resolution]] 1.09&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5qi8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QI8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.09&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GVY:4-(5-amino-1,3,4-thiadiazol-2-yl)phenol'>GVY</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qi8 OCA], [https://pdbe.org/5qi8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qi8 RCSB], [https://www.ebi.ac.uk/pdbsum/5qi8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qi8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.

==See Also==
*[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Brandao-Neto J]]
[[Category: Douangamath A]]
[[Category: Edwards A]]
[[Category: Elkins J]]
[[Category: Kessler B]]
[[Category: Knapp S]]
[[Category: Krojer T]]
[[Category: Schuler H]]
[[Category: Schuller M]]
[[Category: Talon R]]
[[Category: Zhang R]]
[[Category: Von Delft F]]