View source for 5hwc


==Aspergillus fumigatus FKBP12 P90G protein bound with FK506 in P212121 space group==
<StructureSection load='5hwc' size='340' side='right'caption='[[5hwc]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5hwc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus_Af293 Aspergillus fumigatus Af293]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HWC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FK5:8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN'>FK5</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hwc OCA], [https://pdbe.org/5hwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hwc RCSB], [https://www.ebi.ac.uk/pdbsum/5hwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hwc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FKB1A_ASPFU FKB1A_ASPFU] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

==See Also==
*[[FKBP 3D structures|FKBP 3D structures]]
__TOC__
</StructureSection>
[[Category: Aspergillus fumigatus Af293]]
[[Category: Large Structures]]
[[Category: Schumacher MA]]
[[Category: Tonthat NK]]