View source for 4ir0


==Crystal Structure of Metallothiol Transferase FosB 2 from Bacillus anthracis str. Ames==
<StructureSection load='4ir0' size='340' side='right'caption='[[4ir0]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ir0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._Ames Bacillus anthracis str. Ames]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3uh9 3uh9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IR0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FCN:FOSFOMYCIN'>FCN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ir0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ir0 OCA], [https://pdbe.org/4ir0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ir0 RCSB], [https://www.ebi.ac.uk/pdbsum/4ir0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ir0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FOSB2_BACAN FOSB2_BACAN] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.[HAMAP-Rule:MF_01512]

==See Also==
*[[Metallothiol transferase FosB|Metallothiol transferase FosB]]
__TOC__
</StructureSection>
[[Category: Bacillus anthracis str. Ames]]
[[Category: Large Structures]]
[[Category: Anderson WF]]
[[Category: Jedrzejczak R]]
[[Category: Joachimiak A]]
[[Category: Kim Y]]
[[Category: Maltseva N]]
[[Category: Zhang R]]