View source for Hormone

[[Image:1xwd polyview3d.png|right|390px]]
In the field of modern endocrinology, a [[Hormone|hormone]] is any substance, generated either externally or internally, that operates via a receptor at the cellular level, which conveys to to the cell a message to stop, start, or modulate a cellular process.
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==Guide to Proteopedia Pages Concerning Hormones and their Receptors==
{{#tree:id=HormoneTopic|openlevels=0|
Articles in Proteopedia concerning [[Hormone]] include:
<!--* [[Follicle-stimulating hormone]] -->
* [[Hormones and their receptors]]
* [[Steroid Hormones and their receptors]]
* [[Signal transduction]]
* [[Sex steroids]]
* [[Steroids]] 
* [[Human Follicle-Stimulating Hormone Complexed with its Receptor]]
* [[Estrogen receptor]]
* [[Estrogen-related receptor]]
* [[Androgen receptor|Androgen Receptor]]
* [[Leucine-rich repeat|Leucine-rich repeat proteins]]
* [[Human growth hormone]]
* [[Vascular Endothelial Growth Factor]]
* [[Vascular Endothelial Growth Factor Receptor]]
* [[Receiver domain of sensor histidine kinase CKI1]]
* [[Beta-2 Adrenergic Receptor]]
* [[Journal:JBSD:2|Neurotensin]]
* [[Neurotensin receptor]]
* [[Glucagon]]
* [[Glucagon receptor]]
* [[Hormone sensitive lipase]]
* [[Corticosteroid-binding globulin]]
* [[Erythropoietin]]
* [[Erythropoietin receptor]]
* [[Thyroid hormone receptor]]
}}
<br />

To view automatically seeded indices concerning [[Hormone]], see:
*[[:Category:Hormone|Hormone]]
*[[:Category:Hormone receptor|Hormone Receptor]]
*[[:Category:Steroid receptor|Steroid receptor]]
*[[:Category:Steroid hormone receptor|Steroid hormone receptor]]
<br />

==Additional 3D Structures of Hormones and Hormone Receptors and Related Molecules==

===Adrenaline===
[[Image:7tm labeled.png|right|400px]]
[[Beta-2 Adrenergic Receptor]]<br />
The human β2 adrenergic receptor bound to a [[hormone]] analog and G-protein ([[3sn6]]) is featured in an image on the right, and additional structures are on the [[Adrenergic receptor|Adrenergic receptor page]]. <br />
{{Template:GPCR3sn6}}

===Angiotensinogen===
[[Serpin]]  

===Chorionic Gonadotropin===

[[1hrp]], [[1hcn]] - hCG – human<br />
[[1hd4]] - α-subunit of hCG <br />
[[1e9j]], [[1dz7]] - α-subunit of hCG - NMR<br />
[[1qfw]] - hCG + antibody<br />

=== Estrogen receptor ===
[[Estrogen receptor]]

===Estrogen-related Receptor===
[[Estrogen-related receptor]] 

===Androgen Receptor===
[[Androgen receptor|Nuclear Androgen Receptor]]

===Follicle-Stimulating Hormone===
[[Follicle-stimulating hormone]]

===PACAP/glucagon family of peptide hormones===
[[3n94]] - PAC1R, receptor of pituitary adenylate cyclase activating polypeptide, is a case of a crystal structure disagreeing with the NMR structure [[2jod]] and vice versa <br />
[[2jod]] -  Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular  

===Glucocorticoid===
[[Glucocorticoid receptor]]

===Glucose-dependent Insulinotropic Polypeptide===
[[Glucose-dependent Insulinotropic Polypeptide Receptor]]

===Growth Hormone===
[[Human growth hormone]] is featured [[Human growth hormone|here]].<br />

===Insulin===
[[Insulin]]

===Progesterone ===

[[1a28]] - hProgR steroid-binding domain + progesterone<br />

==See Also==
* [[Cancer]]
* [[Membrane proteins]]
* [[G protein-coupled receptor|G protein-coupled receptors]]
* [[Nobel Prizes for 3D Molecular Structure]]
* [[Highest impact structures]] of all time
* [[Hormones and their receptors]]

==External Resources==
* [http://www.ssfa-gphr.de/index.php Sequence-Structure-Function-Analysis of Glycoprotein Hormone Receptors]
* [http://gris.ulb.ac.be/ GRIS: Glycoprotein-hormone Receptors Information System]
* [http://www.ssfa-7tmr.de/ssfe/ The GPCR-SSFE Database: A Homology Model Resource for G-Protein Coupled Receptors] 
* The [http://www.rcsb.org/pdb/101/motm.do?momID=52 feature on Growth Hormone]   by Shuchismita Dutta and David S. Goodsell for the April 2004 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month].
* [http://proteomics.ucsd.edu/Software/NeuroPedia.html NeuroPedia, a neuropeptide database and spectral library]


[[Category:Topic Page]]
[[Category:Hormone]]
[[Category:Hormones]]
[[Category:Endocrine]]
[[Category:Endocrinology]]
[[Category:Signaling]]
[[Category:Cystine-knot growth factor|Cystine-knot growth factor]]
[[Category:Cyclic cystine knot|Cyclic cystine knot]]
[[Category:Cystine knot superfamily|Cystine knot superfamily]]
[[Category:Cystine knot motif|Cystine knot motif]]