View source for 8toe


==Escherichia coli RNA polymerase unwinding intermediate (I1c) at the lambda PR promoter==
<StructureSection load='8toe' size='340' side='right'caption='[[8toe]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8toe]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Escherichia_phage_Lambda Escherichia phage Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TOE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TOE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1N7:CHAPSO'>1N7</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8toe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8toe OCA], [https://pdbe.org/8toe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8toe RCSB], [https://www.ebi.ac.uk/pdbsum/8toe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8toe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Escherichia phage Lambda]]
[[Category: Large Structures]]
[[Category: Darst SA]]
[[Category: Mueller AU]]
[[Category: Saecker RM]]