View source for 8q37


==Crystal structure of YTHDC1 in complex with Compound 18 (ZA_312)==
<StructureSection load='8q37' size='340' side='right'caption='[[8q37]], [[Resolution|resolution]] 1.28&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8q37]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q37 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.28&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IWF:2-chloranyl-9-[(2-methoxyphenyl)methyl]-~{N}-methyl-purin-6-amine'>IWF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q37 OCA], [https://pdbe.org/8q37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q37 RCSB], [https://www.ebi.ac.uk/pdbsum/8q37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q37 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/YTDC1_HUMAN YTDC1_HUMAN] RNA-binding protein that regulates alternative splice site selection.<ref>PMID:20167602</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bedi RK]]
[[Category: Caflisch A]]
[[Category: Zalesak F]]