View source for 8pvh


==Structure of human apo ALDH1A1 determined by cryoEM at 100 keV==
<StructureSection load='8pvh' size='340' side='right'caption='[[8pvh]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8pvh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PVH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pvh OCA], [https://pdbe.org/8pvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pvh RCSB], [https://www.ebi.ac.uk/pdbsum/8pvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pvh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AL1A1_HUMAN AL1A1_HUMAN] Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity).
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Cannone G]]
[[Category: Chen S]]
[[Category: Dalby J]]
[[Category: Dickerson JL]]
[[Category: El-Gomati MM]]
[[Category: Gittins O]]
[[Category: Henderson R]]
[[Category: Hutchings KA]]
[[Category: Lee Y]]
[[Category: McMullan G]]
[[Category: Meffert M]]
[[Category: Mihaylov D]]
[[Category: Naydenova K]]
[[Category: Peet MJ]]
[[Category: Russo CJ]]
[[Category: Schulze-Briese C]]
[[Category: Sobhy M]]
[[Category: Wells T]]
[[Category: Wilson H]]
[[Category: Yamashita K]]