View source for 8jo2


==Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA==
<StructureSection load='8jo2' size='340' side='right'caption='[[8jo2]], [[Resolution|resolution]] 2.74&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8jo2]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)], [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_JM45 Klebsiella pneumoniae JM45] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JO2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.74&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jo2 OCA], [https://pdbe.org/8jo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jo2 RCSB], [https://www.ebi.ac.uk/pdbsum/8jo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jo2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]

==See Also==
*[[Sigma factor 3D structures|Sigma factor 3D structures]]
__TOC__
</StructureSection>
[[Category: Klebsiella pneumoniae JM45]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Chen C]]
[[Category: Huang H-Y]]
[[Category: Lou Y-C]]
[[Category: Wu K-P]]