View source for 8b20


==NDM-1 metallo-beta-lactamase in complex with triazole-based inhibitor CP57==
<StructureSection load='8b20' size='340' side='right'caption='[[8b20]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8b20]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B20 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B20 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=OQK:2-[(~{E})-[3-sulfanyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]iminomethyl]benzoic+acid'>OQK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b20 OCA], [https://pdbe.org/8b20 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b20 RCSB], [https://www.ebi.ac.uk/pdbsum/8b20 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b20 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/F6IAY7_PSEAI F6IAY7_PSEAI] 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Bersani M]]
[[Category: Cendron L]]
[[Category: Docquier JD]]
[[Category: Gianquinto E]]
[[Category: Lazzarato L]]
[[Category: Spyrakis F]]
[[Category: Tondi D]]
[[Category: Vascon F]]