View source for 8app


==AbLys1 endolysin from Acinetobacter baumannii phage AbTZA1==
<StructureSection load='8app' size='340' side='right'caption='[[8app]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8app]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_phage_AbTZA1 Acinetobacter phage AbTZA1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8APP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8APP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8app FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8app OCA], [https://pdbe.org/8app PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8app RCSB], [https://www.ebi.ac.uk/pdbsum/8app PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8app ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A3T0IGR7_9CAUD A0A3T0IGR7_9CAUD] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.[HAMAP-Rule:MF_04110]

==See Also==
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
__TOC__
</StructureSection>
[[Category: Acinetobacter phage AbTZA1]]
[[Category: Large Structures]]
[[Category: Labrou NE]]
[[Category: Papageorgiou AC]]
[[Category: Premetis GE]]
[[Category: Stathi A]]