View source for 7yz7


==Crystal structure of the zebrafish FoxH1 bound to the TGTGGATT site==
<StructureSection load='7yz7' size='340' side='right'caption='[[7yz7]], [[Resolution|resolution]] 0.98&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7yz7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YZ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YZ7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.98&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yz7 OCA], [https://pdbe.org/7yz7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yz7 RCSB], [https://www.ebi.ac.uk/pdbsum/7yz7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yz7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FOXH1_DANRE FOXH1_DANRE] Transcriptional activator. Activates an activin response element (ARE). Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Modulator of nodal signaling required for organizer formation. Also required for the development of dorsal axial structures and left-right symmetry.<ref>PMID:10996071</ref> <ref>PMID:10996072</ref> 

==See Also==
*[[FOX 3D structures|FOX 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Danio rerio]]
[[Category: Large Structures]]
[[Category: Macias MJ]]
[[Category: Pluta R]]