View source for 7bue


==Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 5.0==
<StructureSection load='7bue' size='340' side='right'caption='[[7bue]], [[Resolution|resolution]] 7.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7bue]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_2 Dengue virus 2] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BUE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BUE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bue FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bue OCA], [https://pdbe.org/7bue PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bue RCSB], [https://www.ebi.ac.uk/pdbsum/7bue PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bue ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/E0WXJ2_9FLAV E0WXJ2_9FLAV] Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host immune response.[ARBA:ARBA00024317]  Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504]  Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]

==See Also==
*[[Antibody 3D structures|Antibody 3D structures]]
__TOC__
</StructureSection>
[[Category: Dengue virus 2]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chew SV]]
[[Category: Kostyuchenko VA]]
[[Category: Lim XN]]
[[Category: Lok SM]]
[[Category: Ng TS]]
[[Category: Zhang S]]