View source for 7bln


==VPS35/VPS29 arch of metazoan membrane-assembled retromer:SNX3 complex modelled with human proteins==
<StructureSection load='7bln' size='340' side='right'caption='[[7bln]], [[Resolution|resolution]] 8.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7bln]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BLN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BLN FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bln FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bln OCA], [https://pdbe.org/7bln PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bln RCSB], [https://www.ebi.ac.uk/pdbsum/7bln PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bln ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VPS29_HUMAN VPS29_HUMAN] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).<ref>PMID:15247922</ref> 

==See Also==
*[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Briggs JAG]]
[[Category: Kovtun O]]
[[Category: Leneva N]]
[[Category: Morado DR]]
[[Category: Owen DJ]]