View source for 7bht


==Crystal structure of MAT2a with quinazolinone fragment 5 bound in the allosteric site==
<StructureSection load='7bht' size='340' side='right'caption='[[7bht]], [[Resolution|resolution]] 1.05&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7bht]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BHT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.052&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=TO8:7-chloranyl-4-(dimethylamino)-1~{H}-quinazolin-2-one'>TO8</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bht OCA], [https://pdbe.org/7bht PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bht RCSB], [https://www.ebi.ac.uk/pdbsum/7bht PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bht ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/METK2_HUMAN METK2_HUMAN] Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

==See Also==
*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Argyrou A]]
[[Category: Bagal S]]
[[Category: Borjesson U]]
[[Category: Cheung T]]
[[Category: Chiarparin E]]
[[Category: Collie I]]
[[Category: De Fusco C]]
[[Category: Evans L]]
[[Category: Grondine M]]
[[Category: Narasimhan P]]
[[Category: Robb G]]
[[Category: Schimpl M]]
[[Category: Scott JS]]
[[Category: Stubbs C]]
[[Category: Tentarelli S]]
[[Category: Underwood E]]
[[Category: Vazquez-Chantada M]]
[[Category: Wagner DJ]]