View source for 6vdm


==HCV NS3/4A protease A156T, D168E double mutant in complex with glecaprevir==
<StructureSection load='6vdm' size='340' side='right'caption='[[6vdm]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VDM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VDM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=O31:(3aR,7S,10S,12R,21E,24aR)-7-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclop+ropyl]-20,20-difluoro-5,8-dioxo-2,3,3a,5,6,7,8,11,12,20,23,24a-dodecahydro-1H,10H-9,12-methanocyclopenta[18,19][1,10,17,+3,6]trioxadiazacyclononadecino[11,12-b]quinoxaline-10-carboxamide'>O31</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vdm OCA], [https://pdbe.org/6vdm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vdm RCSB], [https://www.ebi.ac.uk/pdbsum/6vdm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vdm ProSAT]</span></td></tr>
</table>

==See Also==
*[[Virus protease 3D structures|Virus protease 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Schiffer CA]]
[[Category: Timm J]]