View source for 6mzf


==Structural Basis of Tubulin Recruitment and Assembly by Microtubule Polymerases with Tumor Overexpressed Gene (TOG) Domain Arrays==
<StructureSection load='6mzf' size='340' side='right'caption='[[6mzf]], [[Resolution|resolution]] 4.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6mzf]] is a 28 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Lachancea_kluyveri_NRRL_Y-12651 Lachancea kluyveri NRRL Y-12651] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MZF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mzf OCA], [https://pdbe.org/6mzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mzf RCSB], [https://www.ebi.ac.uk/pdbsum/6mzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mzf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TBA1A_PIG TBA1A_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

==See Also==
*[[Tubulin 3D Structures|Tubulin 3D Structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Lachancea kluyveri NRRL Y-12651]]
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Al-Bassam J]]
[[Category: Nithianantham S]]