View source for 6aj8


==Crystal structure of Trypanosoma brucei glycosomal isocitrate dehydrogenase in complex with NADP+, alpha-ketoglutarate and ca2+==
<StructureSection load='6aj8' size='340' side='right'caption='[[6aj8]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6aj8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AJ8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6aj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aj8 OCA], [https://pdbe.org/6aj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6aj8 RCSB], [https://www.ebi.ac.uk/pdbsum/6aj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6aj8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q387G0_TRYB2 Q387G0_TRYB2] 

==See Also==
*[[Isocitrate dehydrogenase 3D structures|Isocitrate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Allman S]]
[[Category: Balogun EO]]
[[Category: Boshart M]]
[[Category: Bringaud F]]
[[Category: Harada S]]
[[Category: Inaoka DK]]
[[Category: Kita K]]
[[Category: Nozaki T]]
[[Category: Shiba T]]
[[Category: Wang X]]
[[Category: Watanabe Y]]
[[Category: Ziebart N]]