View source for 5u2g


==2.6 Angstrom Resolution Crystal Structure of Penicillin-Binding Protein 1A from Haemophilus influenzae==
<StructureSection load='5u2g' size='340' side='right'caption='[[5u2g]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5u2g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_Rd_KW20 Haemophilus influenzae Rd KW20]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5U2G FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5u2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u2g OCA], [https://pdbe.org/5u2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5u2g RCSB], [https://www.ebi.ac.uk/pdbsum/5u2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5u2g ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PBPA_HAEIN PBPA_HAEIN] Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By similarity).

==See Also==
*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Haemophilus influenzae Rd KW20]]
[[Category: Large Structures]]
[[Category: Anderson WF]]
[[Category: Dubrovska I]]
[[Category: Grimshaw S]]
[[Category: Kiryukhina O]]
[[Category: Kwon K]]
[[Category: Minasov G]]
[[Category: Shuvalova L]]
[[Category: Wawrzak Z]]