View source for 5syc


==Near-atomic resolution cryo-EM reconstruction of peloruside-stabilized microtubule==
<SX load='5syc' size='340' side='right' viewer='molstar' caption='[[5syc]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5syc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SYC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SYC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POU:PELORUSIDE+A'>POU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5syc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5syc OCA], [https://pdbe.org/5syc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5syc RCSB], [https://www.ebi.ac.uk/pdbsum/5syc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5syc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

==See Also==
*[[Tubulin 3D Structures|Tubulin 3D Structures]]
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[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Kellogg EH]]
[[Category: Nogales E]]