View source for 5r63


==PanDDA analysis group deposition -- Crystal Structure of FIBRINOGEN-LIKE GLOBE DOMAIN OF HUMAN TENASCIN-C in complex with Z319545618==
<StructureSection load='5r63' size='340' side='right'caption='[[5r63]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5r63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5R63 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RXS:3-[(2-methyl-1H-imidazol-1-yl)methyl]benzonitrile'>RXS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5r63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r63 OCA], [https://pdbe.org/5r63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5r63 RCSB], [https://www.ebi.ac.uk/pdbsum/5r63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5r63 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TENA_HUMAN TENA_HUMAN] Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bezerra GA]]
[[Category: Bountra C]]
[[Category: Coker JA]]
[[Category: Edwards AM]]
[[Category: Marsden BD]]
[[Category: Yue WW]]
[[Category: Von Delft F]]