View source for 5fhy


==Crystal structure of FliD (HAP2) from Pseudomonas aeruginosa PAO1==
<StructureSection load='5fhy' size='340' side='right'caption='[[5fhy]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5fhy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FHY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.201&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fhy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fhy OCA], [https://pdbe.org/5fhy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fhy RCSB], [https://www.ebi.ac.uk/pdbsum/5fhy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fhy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FLID2_PSEAE FLID2_PSEAE] Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. Essential for motility. Responsible for adhesion to mucin, which is the initial event in colonization by this organism of the airways of cystic fibrosis patients.

==See Also==
*[[Flagellar proteins|Flagellar proteins]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Bonsor D]]
[[Category: Diederichs K]]
[[Category: Postel S]]
[[Category: Sundberg EJ]]