View source for 5fdx


==Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.==
<StructureSection load='5fdx' size='340' side='right'caption='[[5fdx]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5fdx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FDX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5X1:3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-~{N}-[(4~{R})-4-METHYL-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLIN-7-YL]-5-(TRIFLUOROMETHYL)BENZAMIDE'>5X1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdx OCA], [https://pdbe.org/5fdx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fdx RCSB], [https://www.ebi.ac.uk/pdbsum/5fdx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DDR1_HUMAN DDR1_HUMAN] 

==See Also==
*[[Epithelial discoidin domain-containing receptor|Epithelial discoidin domain-containing receptor]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bartual SG]]
[[Category: Borkowska O]]
[[Category: Bountra C]]
[[Category: Bullock A]]
[[Category: Burgess-Brown N]]
[[Category: Chaikuad A]]
[[Category: Chalk R]]
[[Category: Ding K]]
[[Category: Edwards AM]]
[[Category: Kopec J]]
[[Category: Kupinska K]]
[[Category: Mahajan P]]
[[Category: Mukhopadhyay S]]
[[Category: Newman J]]
[[Category: Pinkas DM]]
[[Category: Sorell F]]
[[Category: Strain-Damerell C]]
[[Category: Tallant C]]
[[Category: Talon R]]
[[Category: Wang Z]]
[[Category: Williams E]]
[[Category: Von Delft F]]