View source for 5epf


==Crystal structure of Peroxidoxin BcpB from Mycobacterium tuberculosis==
<StructureSection load='5epf' size='340' side='right'caption='[[5epf]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5epf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EPF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5epf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5epf OCA], [https://pdbe.org/5epf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5epf RCSB], [https://www.ebi.ac.uk/pdbsum/5epf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5epf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BCPB_MYCTU BCPB_MYCTU] Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.[UniProtKB:P0AE52]

==See Also==
*[[Peroxiredoxin 3D structures|Peroxiredoxin 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]