View source for 5ejo


==Crystal structure of the winged helix domain in Chromatin assembly factor 1 subunit p90==
<StructureSection load='5ejo' size='340' side='right'caption='[[5ejo]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5ejo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EJO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EJO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ejo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ejo OCA], [https://pdbe.org/5ejo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ejo RCSB], [https://www.ebi.ac.uk/pdbsum/5ejo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ejo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RLF2_YEAST RLF2_YEAST] Acts as a component of chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto replicating DNA in vitro. It performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. p90 may facilitate the efficient and timely assembly of histones into telomeric chromatin.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Burgess R]]
[[Category: Gao Y]]
[[Category: Han J]]
[[Category: Li J]]
[[Category: Liang H]]
[[Category: Liu Y]]
[[Category: Zhang K]]
[[Category: Zhang Z]]