View source for 4xfp


==Crystal Structure of Highly Active Mutant of Bacillus sp. TB-90 Urate Oxidase==
<StructureSection load='4xfp' size='340' side='right'caption='[[4xfp]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4xfp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._TB-90 Bacillus sp. TB-90]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XFP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.66&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xfp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xfp OCA], [https://pdbe.org/4xfp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xfp RCSB], [https://www.ebi.ac.uk/pdbsum/4xfp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xfp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PUCL_BACSB PUCL_BACSB] Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin (By similarity).

==See Also==
*[[Urate oxidase 3D structures|Urate oxidase 3D structures]]
__TOC__
</StructureSection>
[[Category: Bacillus sp. TB-90]]
[[Category: Large Structures]]
[[Category: Hayashi Y]]
[[Category: Hibi T]]
[[Category: Itoh T]]
[[Category: Kawamura A]]