View source for 4mpg


==Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target EFI-507257==
<StructureSection load='4mpg' size='340' side='right'caption='[[4mpg]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4mpg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MPG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.951&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mpg OCA], [https://pdbe.org/4mpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mpg RCSB], [https://www.ebi.ac.uk/pdbsum/4mpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mpg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GSTT2_HUMAN GSTT2_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity.

==See Also==
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Al Obaidi N]]
[[Category: Almo SC]]
[[Category: Armstrong RN]]
[[Category: Bhosle R]]
[[Category: Chowdhury S]]
[[Category: Evans B]]
[[Category: Gerlt JA]]
[[Category: Hammonds J]]
[[Category: Hillerich B]]
[[Category: Imker HJ]]
[[Category: Love J]]
[[Category: Patskovsky Y]]
[[Category: Scott Glenn A]]
[[Category: Seidel RD]]
[[Category: Stead M]]
[[Category: Toro R]]
[[Category: Washington E]]