View source for 4f60


==Crystal structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant (T148L, G171Q, A172V, C176F).==
<StructureSection load='4f60' size='340' side='right'caption='[[4f60]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4f60]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_rhodochrous Rhodococcus rhodochrous]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F60 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F:FLUORIDE+ION'>F</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f60 OCA], [https://pdbe.org/4f60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f60 RCSB], [https://www.ebi.ac.uk/pdbsum/4f60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f60 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane.

==See Also==
*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rhodococcus rhodochrous]]
[[Category: Kuta-Smatanova I]]
[[Category: Plevaka M]]
[[Category: Rezacova P]]