View source for 4e14


==Crystal structure of kynurenine formamidase conjugated with phenylmethylsulfonyl fluoride==
<StructureSection load='4e14' size='340' side='right'caption='[[4e14]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4e14]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E14 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E14 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SEB:O-BENZYLSULFONYL-SERINE'>SEB</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e14 OCA], [https://pdbe.org/4e14 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e14 RCSB], [https://www.ebi.ac.uk/pdbsum/4e14 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e14 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KFA_DROME KFA_DROME] Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.[HAMAP-Rule:MF_03014]<ref>PMID:22690733</ref> <ref>PMID:83140</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Han Q]]
[[Category: Li J]]
[[Category: Robinson H]]