View source for 4dwj


==Crystal structure of Thymidylate Kinase from Staphylococcus aureus in complex with Thymidine Monophosphate==
<StructureSection load='4dwj' size='340' side='right'caption='[[4dwj]], [[Resolution|resolution]] 2.74&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4dwj]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DWJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.74&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TMP:THYMIDINE-5-PHOSPHATE'>TMP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dwj OCA], [https://pdbe.org/4dwj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dwj RCSB], [https://www.ebi.ac.uk/pdbsum/4dwj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dwj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KTHY_STAAM KTHY_STAAM] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity).

==See Also==
*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus subsp. aureus Mu50]]
[[Category: Anderson WF]]
[[Category: Babnigg G]]
[[Category: Filippova EV]]
[[Category: Jedrzejczak R]]
[[Category: Joachimiak A]]
[[Category: Kiryukhina O]]
[[Category: Minasov G]]
[[Category: Rubin E]]
[[Category: Sacchettini J]]
[[Category: Shuvalova L]]