View source for 4dix


==Crystal structure of the Ig-PH domain of actin-binding protein SCAB1==
<StructureSection load='4dix' size='340' side='right'caption='[[4dix]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4dix]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DIX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dix OCA], [https://pdbe.org/4dix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dix RCSB], [https://www.ebi.ac.uk/pdbsum/4dix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dix ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SCAB1_ARATH SCAB1_ARATH] Plant-specific actin binding protein that bundles and stabilizes microfilaments (MFs). Has no nucleation or capping activity. Regulates MF reorganization during stomatal closure. The binding to F-actin is insensitive to Ca(2+) and pH. Binds weakly to inositol phosphates (PubMed:22356912).<ref>PMID:21719691</ref> <ref>PMID:22356912</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Ye K]]
[[Category: Zhang W]]