View source for 3vmm


==Crystal structure of BacD, an L-amino acid dipeptide ligase from Bacillus subtilis==
<StructureSection load='3vmm' size='340' side='right'caption='[[3vmm]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3vmm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VMM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=P0D:(2S)-3-[(S)-[(1R)-1-AMINOETHYL](PHOSPHONOOXY)PHOSPHORYL]-2-BENZYLPROPANOIC+ACID'>P0D</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vmm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vmm OCA], [https://pdbe.org/3vmm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vmm RCSB], [https://www.ebi.ac.uk/pdbsum/3vmm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vmm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BACD_BACSU BACD_BACSU] Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. Has a broad substrate specificity. Does not accept lysine, arginine, glutamate, aspartate and proline as a substrate. Probably catalyzes the ligation of L-alanine and L-anticapsin to produce the final bacilysin antibiotic.
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Higuchi Y]]
[[Category: Shomura Y]]