View source for 3unw


==Crystal Structure of Human GAC in Complex with Glutamate==
<StructureSection load='3unw' size='340' side='right'caption='[[3unw]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3unw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UNW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3unw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3unw OCA], [https://pdbe.org/3unw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3unw RCSB], [https://www.ebi.ac.uk/pdbsum/3unw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3unw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.

==See Also==
*[[Glutaminase|Glutaminase]]
*[[Glutaminase 3D structures|Glutaminase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Cheng F]]
[[Category: DeLaBarre B]]
[[Category: Gao Y]]
[[Category: Gross S]]
[[Category: Hurov J]]
[[Category: Jha A]]
[[Category: Jiang F]]
[[Category: Song JJ]]
[[Category: Wie W]]