View source for 3sl1


==Crystal Structure of P. falciparum arginase complexed with 2-amino-6-borono-2-methylhexanoic acid==
<StructureSection load='3sl1' size='340' side='right'caption='[[3sl1]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3sl1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SL1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.902&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FB6:6-(DIHYDROXYBORANYL)-2-METHYL-L-NORLEUCINE'>FB6</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sl1 OCA], [https://pdbe.org/3sl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sl1 RCSB], [https://www.ebi.ac.uk/pdbsum/3sl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sl1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARGI_PLAF7 ARGI_PLAF7] Catalyzes the hydrolysis of L-arginine into urea and L-ornithine, which is a precursor for polyamine biosynthesis (PubMed:15843155, PubMed:19456858, PubMed:20527960, PubMed:21728378). May play a role in parasite intra-hepatic development during the host liver stage (By similarity).[UniProtKB:A0A509AF89]<ref>PMID:15843155</ref> <ref>PMID:19456858</ref> <ref>PMID:20527960</ref> <ref>PMID:21728378</ref> 

==See Also==
*[[Arginase 3D structures|Arginase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Plasmodium falciparum 3D7]]
[[Category: Christianson DW]]
[[Category: Dowling DP]]
[[Category: Ilies M]]