View source for 3ky7


==2.35 Angstrom resolution crystal structure of a putative tRNA (guanine-7-)-methyltransferase (trmD) from Staphylococcus aureus subsp. aureus MRSA252==
<StructureSection load='3ky7' size='340' side='right' caption='[[3ky7]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ky7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staar Staar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KY7 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SAR1216, trmD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=282458 STAAR])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.221 and 2.1.1.228 2.1.1.221 and 2.1.1.228] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ky7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ky7 OCA], [http://pdbe.org/3ky7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ky7 RCSB], [http://www.ebi.ac.uk/pdbsum/3ky7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ky7 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/TRMD_STAAR TRMD_STAAR]] Specifically methylates guanosine-37 in various tRNAs (By similarity). 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ky/3ky7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ky7 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Staar]]
[[Category: Transferase]]
[[Category: Anderson, W F]]
[[Category: Structural genomic]]
[[Category: Dubrovska, I]]
[[Category: Halavaty, A S]]
[[Category: Minasov, G]]
[[Category: Reiner, N]]
[[Category: See, R]]
[[Category: Shuvalova, L]]
[[Category: Winsor, J]]
[[Category: Zoraghi, R]]
[[Category: Csgid]]
[[Category: Infectious disease]]
[[Category: Methyltransferase]]
[[Category: S-adenosyl-l-methionine]]
[[Category: Trna processing]]