View source for 3hxp


==Crystal structure of the FhuD fold-family BSU3320, a periplasmic binding protein component of a Fep/Fec-like ferrichrome ABC transporter from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR577==
<StructureSection load='3hxp' size='340' side='right'caption='[[3hxp]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3hxp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HXP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hxp OCA], [https://pdbe.org/3hxp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hxp RCSB], [https://www.ebi.ac.uk/pdbsum/3hxp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hxp ProSAT], [https://www.topsan.org/Proteins/NESGC/3hxp TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FHUD_BACSU FHUD_BACSU] Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen.<ref>PMID:8388528</ref> <ref>PMID:16672620</ref> 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/3hxp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hxp ConSurf].
<div style="clear:both"></div>

==See Also==
*[[ABC transporter 3D structures|ABC transporter 3D structures]]
*[[Ferric hydroxamate uptake receptor|Ferric hydroxamate uptake receptor]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Acton TB]]
[[Category: Chen CX]]
[[Category: Cunningham K]]
[[Category: Everett JK]]
[[Category: Fang F]]
[[Category: Forouhar F]]
[[Category: Hunt JF]]
[[Category: Ma L]]
[[Category: Montelione GT]]
[[Category: Nair R]]
[[Category: Neely H]]
[[Category: Rost B]]
[[Category: Seetharaman J]]
[[Category: Tong L]]
[[Category: Xiao R]]