View source for 2xio


==Structure of putative deoxyribonuclease TATDN1 isoform a==
<StructureSection load='2xio' size='340' side='right'caption='[[2xio]], [[Resolution|resolution]] 1.19&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2xio]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XIO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xio OCA], [https://pdbe.org/2xio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xio RCSB], [https://www.ebi.ac.uk/pdbsum/2xio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xio ProSAT]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/TATD1_HUMAN TATD1_HUMAN]] Putative deoxyribonuclease (By similarity). 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xi/2xio_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xio ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Cocking, R]]
[[Category: Delft, F von]]
[[Category: Edwards, A M]]
[[Category: Kavanagh, K L]]
[[Category: Krojer, T]]
[[Category: Muniz, J R.C]]
[[Category: Oppermann, U]]
[[Category: Puranik, S]]
[[Category: Raynor, J]]
[[Category: Vollmar, M]]
[[Category: Weigelt, J]]
[[Category: Yue, W W]]
[[Category: Hydrolase]]
[[Category: Nuclease]]