View source for 2rs2


==1H, 13C, and 15N Chemical Shift Assignments for Musashi1 RBD1:r(GUAGU) complex==
<StructureSection load='2rs2' size='340' side='right'caption='[[2rs2]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2rs2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RS2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rs2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rs2 OCA], [https://pdbe.org/2rs2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rs2 RCSB], [https://www.ebi.ac.uk/pdbsum/2rs2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rs2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MSI1H_MOUSE MSI1H_MOUSE] RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.<ref>PMID:11359897</ref> <ref>PMID:12407178</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Imai T]]
[[Category: Katahira M]]
[[Category: Nagata T]]
[[Category: Ohyama T]]
[[Category: Okano H]]
[[Category: Tsuda K]]
[[Category: Yamazaki T]]