View source for 2fvo


==Docking of the modified RF1 X-ray structure into the Low Resolution Cryo-EM map of E.coli 70S Ribosome bound with RF1==
<SX load='2fvo' size='340' side='right' viewer='molstar' caption='[[2fvo]], [[Resolution|resolution]] 12.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2fvo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FVO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FVO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 12.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fvo OCA], [https://pdbe.org/2fvo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fvo RCSB], [https://www.ebi.ac.uk/pdbsum/2fvo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fvo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RF1_THEMA RF1_THEMA] Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/2fvo_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fvo ConSurf].
<div style="clear:both"></div>
__TOC__
</SX>
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Ehrenberg M]]
[[Category: Frank J]]
[[Category: Gao H]]
[[Category: Gursky R]]
[[Category: Rawat U]]
[[Category: Zavialov A]]