View source for 2bei


==X-ray structure of thialysine n-acetyltransferase (SSAT2) from homo sapiens==
<StructureSection load='2bei' size='340' side='right'caption='[[2bei]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2bei]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BEI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.842&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bei OCA], [https://pdbe.org/2bei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bei RCSB], [https://www.ebi.ac.uk/pdbsum/2bei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bei ProSAT], [https://www.topsan.org/Proteins/CESG/2bei TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SAT2_HUMAN SAT2_HUMAN] Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine > spermidine = spermine >> N(1)acetylspermine = putrescine.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/be/2bei_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bei ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Spermidine/spermine N-acetyltransferase|Spermidine/spermine N-acetyltransferase]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bae E]]
[[Category: Bingman CA]]
[[Category: Bitto E]]
[[Category: Han BW]]
[[Category: Phillips Jr GN]]
[[Category: Wesenberg GE]]