View source for 1e8l


==NMR solution structure of hen lysozyme==
<StructureSection load='1e8l' size='340' side='right'caption='[[1e8l]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1e8l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hwa 1hwa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E8L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E8L FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e8l OCA], [https://pdbe.org/1e8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e8l RCSB], [https://www.ebi.ac.uk/pdbsum/1e8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e8l ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e8/1e8l_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e8l ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Boyd J]]
[[Category: Buck M]]
[[Category: Dobson CM]]
[[Category: Grimshaw SB]]
[[Category: Redfield C]]
[[Category: Schwalbe H]]
[[Category: Smith LJ]]
[[Category: Spencer A]]