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:
STRUCTURE 1h8f
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Asymmetric Unit
Biological Assembly
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1h8f
,
resolution
2.80Å (
)
Ligands
:
Activity
:
Non-specific serine/threonine protein kinase
, with EC number
2.7.11.1
Structural annotation
:
Resources:
CATH :
1H8Fa02
,
1H8Fa01
,
1H8Fb02
,
1H8Fb01
InterPro :
Ipr011009
,
Ipr000719
,
Ipr008271
,
Ipr002290
Pfam :
PF00069
SCOP :
d1h8fa_
,
d1h8fb_
UniProt :
P49841
Functional annotation
:
Cellular component
:
cytoplasm
nucleus
beta-catenin destruction complex
Biological process
:
positive regulation of protein export from nucleus
peptidyl-serine phosphorylation
Wnt receptor signaling pathway through beta-catenin
ER overload response
Wnt receptor signaling pathway
negative regulation of apoptosis
protein amino acid phosphorylation
intracellular signaling cascade
glycogen metabolic process
Molecular function
:
nucleotide binding
ATP binding
transferase activity
p53 binding
NF-kappaB binding
kinase activity
protein serine/threonine kinase activity
protein kinase activity
protein binding
glycogen synthase kinase 3 activity
Evolutionary conservation
:
Toggle Conservation Colors:
Further Information:
Caveats
,
Explanation
,
Complete Results at ConSurfDB
Resources:
FirstGlance
,
OCA
,
RCSB
,
PDBsum
Coordinates
:
save as
pdb
,
mmCIF
,
xml
proteopedia link