Sulfurtransferase

Function Sulfurtransferase (ST) are enzymes which transfer sulfur-containing groups. Thiosulfate ST (TST) catalyzes the conversion of thiosulfate and cyanide to sulfite and thiocyanate. Mercaptopyruvate ST (MST) transfers sulfate from mercaptopyruvate. Relevance Inhibitors of MST suppress H2S production and this make non sulfur bacteria like E. coli and Bacillus anthracis sensitive to antibiotics. Structural highlights The . Water molecules are shown as red spheres.

spinqualitylabelsall models Human mercaptopyruvate sulfurtransferase with mercaptocysteine complex with pyruvate, sulfate (PDB entry 4jgt) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of sulfurtransferase3D Structures of sulfurtransferase

Updated on 01-March-2024

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• Sulfurtransferase
  • 1boh, 1boi, 1orb, 1rhd, 1rhs – bST – bovine
    
  • 1dp2 – bST + lipoate
    
  • 3lvj, 3lvk – EcST TusA + cysteine desulfurase - Escherichia coli
    
  • 2fsx – MtST – Mycobacterium tuberculosis
    
  • 1uar – ST – Thermus thermophilus
    
  • 6ktx, 6h99 – ClST – Chlorobium limicola
    
  • 6ku1, 6ku2, 6kw0 – ClST (mutant) + ergothioneine
    
  • 6h9a, 6ktv, 6ktw – ClST + hercynine
    
  • 6kvz, 6kvy, 6kvw, 6ktz – ClST (mutant) + hercynine
    
  • 7syb – ST – Acinetobacter baumanni
    
• Mercaptopyruvate sulfurtransferase
  • 3olh, 4jgt – MST - human
    
  • 5wqj, 5wqk – MST (mutant) + inhibitor – mouse
    
  • 1okg – MST (mutant) – Leishmania major
  • 1urh – EcMST
  • 5wqj, 5wqk – MST + inhibitor - mouse
    
• Thiosulfate sulfurtransferase or rhodanese
  • 6bev – hTST D1
    
  • 2ora, 8q5z – bTST
    
  • 3utn – yTST Tum1 – yeast
    
  • 6k6r – yTST Rdl2
    
  • 1yt8 – TST – Pseudomonas aeruginosa
    
  • 3hwi, 3p3a – MtTST
    
  • 3hzu – MtTST Ssea
    
  • 1e0c – AvST – Azotobacter vinelandii
    
  • 1gmx, 1gn0 – EcST Glpe
    
• Zinc-dependent sulfurtransferase SufU
  • 6jzv, 6jzw – BsZST + Zn – Bacillus subtilis
    
  • 5xt5 – BsZST + Zn + PLP
    
  • 5xt6 – BsZST + cysteine desulferase + Zn + PLP derivative
    
  • 1h4k – AvZST + hypophosphite
  • 1h4m – AvZST + phosphate