Ribosomal protein L27

Function

Ribosomal protein L27 (RPL27) is one of the 34 proteins which belong to the large 50S subunit of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. RPL27 is located at the interface between the small and large subunits.

Relevance

RPL27 from Trypanosoma cruzi may be involved in Chagas disease[1].


Ribosomal protein L27 complex with DTT (PDB code 1v8q)

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3D Structures of Ribosomal protein L273D Structures of Ribosomal protein L27

Updated on 01-October-2017

1v8q – TtRPL27 - Thermus thermophilus
1y69 – RPL27 + RPL16 + ribosome recycling factor + 5S RRNA + 23S RRNA – Deinococcus radiodurans

ReferencesReferences

  1. Perone D, Santos MA, Peixoto MS, Cicarelli RM. Trypanosoma cruzi: identification and characterization of a novel ribosomal protein L27 (TcrL27) that cross-reacts with an affinity-purified anti-Sm antibody. Parasitology. 2003 Jun;126(Pt 6):577-83. PMID:12866796

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Michal Harel, Alexander Berchansky, Joel L. Sussman