Ribosomal protein L21

Function

Ribosomal protein L21 (RPL21) is one of the 34 proteins which belong to the of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. RPL21 binds to 23S RRNA in the presence of RPL20^[1].

Disease

Mutation in RPL21 underlie hereditary hypotrichosis simplex^[2].

ReferencesReferences

↑ Yin T, Pan G, Liu H, Wu J, Li Y, Zhao Z, Fu T, Zhou Y. The chloroplast ribosomal protein L21 gene is essential for plastid development and embryogenesis in Arabidopsis. Planta. 2012 May;235(5):907-21. doi: 10.1007/s00425-011-1547-0. Epub 2011 Nov 22. PMID:22105802 doi:http://dx.doi.org/10.1007/s00425-011-1547-0
↑ Zhou C, Zang D, Jin Y, Wu H, Liu Z, Du J, Zhang J. Mutation in ribosomal protein L21 underlies hereditary hypotrichosis simplex. Hum Mutat. 2011 Jul;32(7):710-4. doi: 10.1002/humu.21503. Epub 2011 Apr 26. PMID:21412954 doi:10.1002/humu.21503

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Michal Harel, Alexander Berchansky, Joel L. Sussman

[1] Yin T, Pan G, Liu H, Wu J, Li Y, Zhao Z, Fu T, Zhou Y. The chloroplast ribosomal protein L21 gene is essential for plastid development and embryogenesis in Arabidopsis. Planta. 2012 May;235(5):907-21. doi: 10.1007/s00425-011-1547-0. Epub 2011 Nov 22. PMID:22105802 doi:http://dx.doi.org/10.1007/s00425-011-1547-0

[2] Zhou C, Zang D, Jin Y, Wu H, Liu Z, Du J, Zhang J. Mutation in ribosomal protein L21 underlies hereditary hypotrichosis simplex. Hum Mutat. 2011 Jul;32(7):710-4. doi: 10.1002/humu.21503. Epub 2011 Apr 26. PMID:21412954 doi:10.1002/humu.21503

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