Pyridoxal kinase

Function Pyridoxal kinase (PDX) catalyzes the transfer of phosphate (Pi) from ATP to 5’ alcohol of pyridoxine, pyridoxamine and pyridoxal. Structural highlights .

spinqualitylabelsall models E. Coli pyridoxal kinase 1 complex with pyridoxal 2ddw Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of pyridoxal kinase3D Structures of pyridoxal kinase

Updated on 04-October-2023

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• Pyridoxal kinase
  • 2f7k – hPDX - human
    
  • 1lhp – sPDX – sheep
    
  • 6yjz – mPDX - mouse
    
  • 2ddm – EcPDX1 – Escherichia coli
    
  • 3h74 – LpPDX – Lactobacillus planarum
    
  • 3zs7 – PDX – Trypanosoma brucei
    
  • 4c5j – SaPDX – Staphylococcus aureus
    
  • 5tqi - PDX - Burkholderia multivorans
    
  • 5trw - PDX - Burkholderia xenovorans
    
  • 5b6a - PDX - Pseudomonas aeruginosa
    
  • 5zw9 – ScPDX – Salmonella choleraesuis
    
• Pyridoxal kinase complex with pyridoxal compounds
  • 3fhx – hPDX (mutant) + Mg + Na + ATP + pyridoxal + PLP
    
  • 3keu – hPDX + Mg + ATP + PLP
    
  • 1rft – sPDX + Zn + K + AMPPCP + pyridoxamine
    
  • 1rfu – sPDX + Zn + ADP + PLP
    
  • 2ddw – EcPDX1 + pyridoxal
    
  • 4c5l – SaPDX + pyridoxal
    
  • 4c5n – SaPDX + pyridoxal + AMPPCP
    
  • 4s1i – EhPDX + Mg + PLP - Entamoeba histolytica
    
  • 6su9 – PDX + pyridoxal + AMPPNP – Plasmodium falciparum
    
  • 6k91, 6k92 – LdPDX + ADP + pyridoxine derivative – Leishmania donovani
    
  • 6k90 – LdPDX + ADP + pyridoxamine
    
  • 5zwa, 5zwb – ScPDX + ADP + PLP
    
• Other pyridoxal kinase complexes
  • 2ajp – hPDX + Mg + ANP
    
  • 2yxt – hPDX + Na + Pi
    
  • 2yxu – hPDX + Mg + Na + ATP + Pi
    
  • 3fhy – hPDX (mutant) + Mg + Na + ATP
    
  • 4en4 – hPDX + Mg + ATP + ginkotoxin
    
  • 4eoh – hPDX + Na + theophylline
    
  • 1lhr – sPDX + Zn + K + ATP
    
  • 1rfv – sPDX + Zn + ADP
    
  • 1ygj, 1ygk, 1yhj – sPDX + roscovitine
    
  • 6yk0 – mPDX + ATPgS
    
  • 6yk1 – mPDX + ATPgS + artesunate
    
  • 2ddo – EcPDX1 + Mg + ATP + Pi
    
  • 2i5b – PDX + ADP – Bacillus subtilis
    
  • 6k8z – LdPDX + ADP
    
  • 3hyo – LpPDX + Mg + ADP
    
  • 3ibq – LpPDX + Mg + ATP
    
  • 4c5k – SaPDX + ADP
    
  • 4c5m – SaPDX + AMPPCP
    
  • 4s1m – EhPDX + Mg
    
  • 4s1h – EhPDX + Mg + ADP