Protein Transport Membrane Protein

Structure Highlights

The PDB code of the protein transport membrane protein is 3q5u.

Protein transport membrane protein is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance

Related:1Y2A (OCA)
Resources:OCA, RCSB

A membrane transport protein (or simply transporter) is a membrane protein involved in the movement of ions, small molecules, or macromolecules, such as another protein, across a biological membrane. Transport proteins are integral transmembrane proteins; that is they exist permanently within and span the membrane across which they transport substances. The proteins may assist in the movement of substances by facilitated diffusion or active transport. These mechanisms of action are known as carrier-mediated transport.

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3D structure

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3D structures of importin

Importin

Publication Abstract from PubMed

A minimal NLS in human phospholipid scramblase 4 that binds only the minor NLS-binding site of importin {alpha}1., Lott K, Bhardwaj A, Sims PJ, Cingolani G, J Biol Chem. 2011 Jun 20. [1]

References

  1. Lott K, Bhardwaj A, Sims PJ, Cingolani G. A minimal NLS in human phospholipid scramblase 4 that binds only the minor NLS-binding site of importin {alpha}1. J Biol Chem. 2011 Jun 20. PMID:21690087 doi:10.1074/jbc.M111.228007






Mouse importin subunit α-2 (grey) complex with human phospholipid scramblase 4 peptide (green) (PDB code 3q5u).

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Ma Zhuang, Michal Harel