Propranolol
Propranolol, sold under the brand name Inderal among others, is a medication of the beta blocker class.[1] It is used to treat high blood pressure, a number of types of irregular heart rate, thyrotoxicosis, capillary hemangiomas, performance anxiety, and essential tremors,[1][2][3] as well to prevent migraine headaches, and to prevent further heart problems in those with angina or previous heart attacks.[1] It can be taken orally (by mouth) or by intravenous injection (injection into a vein).[1] See also Propranolol and Adrenergic receptor. Propranolol is classified as a competitive non-cardioselective sympatholytic beta blocker that crosses the blood–brain barrier. It is lipid soluble and also has sodium channel blocking effects. Propranolol is a non-selective β-adrenergic receptor antagonist, or beta blocker; that is, it blocks the action of epinephrine (adrenaline) and norepinephrine (noradrenaline) at both β1- and β2-adrenergic receptors.[4]
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ReferencesReferences
- ↑ 1.0 1.1 1.2 1.3 "Propranolol hydrochloride". Monograph. The American Society of Health-System Pharmacists. Archived from the original on 1 January 2015. Retrieved 1 January 2015.
- ↑ Davidson JR. Pharmacotherapy of social anxiety disorder: what does the evidence tell us? J Clin Psychiatry. 2006;67 Suppl 12:20-6 PMID:17092192
- ↑ Chinnadurai S, Fonnesbeck C, Snyder KM, Sathe NA, Morad A, Likis FE, McPheeters ML. Pharmacologic Interventions for Infantile Hemangioma: A Meta-analysis. Pediatrics. 2016 Feb;137(2):e20153896. PMID:26772662 doi:10.1542/peds.2015-3896
- ↑ Al-Majed AA, Bakheit AHH, Abdel Aziz HA, Alajmi FM, AlRabiah H. Propranolol. Profiles Drug Subst Excip Relat Methodol. 2017;42:287-338. PMID:28431779 doi:10.1016/bs.podrm.2017.02.006