Hypertension & Congestive Heart Failure

Hypertension & Congestive Heart Failure are disorders of the circulatory system. Hypertension, also known as "high blood pressure" occurs when systemic arterial blood pressure is elevated. It is a major risk factor for stroke and heart failure. Congestive Heart Failure is the most common type of heart failure is marked by low cardiac output.

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Articles in Proteopedia concerning Hypertension & Congestive Heart Failure include:

• Angiotensin-Converting Enzyme
• Calcium Channels

To view Hypertension & Congestive Heart Failure related proteins which are Structure Index entries see:

• Angiotensin-Converting Enzymes
• Ouabain is a cardiac glycoside that inhibits ATP-dependent sodium-potassium exchange across cell membranes. The binding of ouabain to the sodium-potassium pump (also called Na+/K+ ATPase) prevents the conformational changes necessary for its proper function.

• Renin is important clinically because renin inhibitors, such as aliskiren, can be used to treat hypertension. Aliskiren is approved by the Federal Drug Administration (FDA) to treat hypertension.

To view automatically seeded pages concerning Hypertension & Congestive Heart Failure See:

• Hypertension
• Ion Channel

To View FDA Approved Treatments for Hypertension & Congestive Heart Failure See: Treatments

To view other Proteopedia pages about diseases & drug targets, See: Pharmaceutical Drug Targets