Haloperoxidase

Function Haloperoxidases catalyze the oxidation of halides by hydrogen peroxide while adding a halide to hydrocarbons. They are classified as chloroperoxldase (CPO), bromoperoxidase (BPO) and iodoperoxidase (IPO) according to the halide which they oxidize. CPO is heme-containing, vanadium-containing or metal-free. BPO is from marine algae is vanadium-containing. Structural highlights The . The iodine atoms are coordinated to tyrosine residues: and . Water molecules shown as red spheres.

spinqualitylabelsall models Bromoperoxidase complex with VO4 and I- (purple) ions, 1qi9 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of haloperoxidase3D structures of haloperoxidase

Updated on 30-June-2024

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• Vanadium-dependent chloroperoxidase
  • 1vnc, 1vni, 1idq, 1idu – CiCPO + VO4 – Curvularia inaequalis
    
  • 1vne, 1vnf, 1vng, 1vnh – CiCPO (mutant) + VO4
    
  • 1vns, 3bb0 – CiCPO
    
  • 3w35 – StCPO – Streptomyces
    
  • 3w36 – StCPO + VO4
    
  • 5lpc – CPO – Acaryochloris marina
    
• Heme-containing chloroperoxidase
  • 1cpo, 2cpo – LfCPO – Leptoxyphium fumago
    
  • 2civ, 2j18, 2j19 – LfCPO + Br
    
  • 2ciw – LfCPO + I
    
  • 2cix – LfCPO + cyclopentane-dione + Br
    
  • 2ciy – LfCPO + CN + DMSO + Br
    
  • 2ciz – LfCPO + acetate + Br
    
  • 2cj0 – LfCPO + nitrate
    
  • 2cj1, 2cj2 – LfCPO + formate
    
  • 2j5m – LfCPO + H2O2
• Metal-free chloroperoxidase
  • 1a7u - SaCPO T – Streptomyces aureofaciens
    
  • 1a8s – PfCPO F + propanoic acid – Pseudomonas fluorescens
    
  • 1a8u – PfCPO T + benzoic acid
    
  • 1a88 - CPO L – Streptomyces lividans
    
  • 4dgq – CPO – Burkholderia cenocepacia
    
• Metal-free bromoperoxidase
  • 1a8q – SaBPO A1
    
  • 1bro - SaBPO A2
    
  • 1brt, 4iq4, 4itv, 4ivj, 4qes, 4qf0, 4qff – SaBPO A2 (mutant)
    
  • 3fob – BPO – Bacillus anthracis
• Vanadium-containing bromoperoxidase
  • 1qi9 – AnBPO + I + VO4 – Ascophyllum nodosum
    
  • 5aa6 – AnBPO-2 + VO4
    
  • 1up8, 1qhb, 7qyy – CpBPO – Corallina pilulifera
    
  • 7qvw – CpBPO (mutant)
    
  • 7qwi – CpBPO + VO4
    
  • 7qw3 – CpBPO (mutant) + Br
    
• Vanadium-containing iodoperoxidase
  • 4cit, 4usz – IPO + VO4 – Zobellia galactanivorans