GABAA receptor

GABAA receptors, which are considered ligand-gated ion channels as the binding of GABA results in the opening of ion channels leading to the inhibition of a neuronal signal. Excitatory neurosteroids have excitatory effects on neurotransmission. They act as potent negative allosteric modulators of the GABAA receptor. Major examples include the pregnanes pregnenolone sulfate (PS), epipregnanolone, and isopregnanolone (sepranolone). . (5o8f). . See also: GABA receptor Steroids Neurosteroids Inhibitory neurosteroids Excitatory neurosteroids

spinqualitylabelsall models Structure of a chimaeric beta3-alpha5 GABAA receptor in complex with pregnanolone (based on 5o8f) scene= Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

GABAA receptor 3D structuresGABAA receptor 3D structures

See GABA receptor 3D structures